5-Hydroxytryptophan Powder Raw Material
99%+ Purity • Griffonia Simplicifolia Extract • Premium Bulk Raw Material for Nutraceutical Formulation
High-purity 5-Hydroxytryptophan Powder – the direct natural precursor to 5-Hydroxytryptamine (serotonin, or 5-HT). Also known as 5-HTP (L-5-Hydroxytryptophan or oxitriptan), this premium raw material is ideal for dietary supplement manufacturers, formulators, encapsulation, and custom blending. It supports the body’s natural production of serotonin, the key neurotransmitter that regulates mood, sleep, appetite, and emotional balance.
Scientific Profile
- Scientific Name : 5-Hydroxytryptophan (L-5-Hydroxytryptophan is the biologically active isomer).
- Molecular Formula: C₁₁H₁₂N₂O₃
- Molecular Weight: 220.22 g/mol
- CAS Number: 56-69-9
- Key Characteristics: Naturally occurring amino acid and metabolic intermediate in the serotonin biosynthesis pathway. Extracted from the seeds of the African plant Griffonia simplicifolia. Appears as a white to off-white crystalline powder, stable, water-soluble, and uniquely capable of crossing the blood-brain barrier (unlike serotonin itself). It is rapidly converted into serotonin in the brain with the assistance of vitamin B6 (pyridoxal phosphate) via the enzyme aromatic L-amino acid decarboxylase.
- Key Features: 99%+ purity (HPLC tested), non-GMO, vegan source, gluten-free, no artificial additives. Bypasses the rate-limiting step of tryptophan hydroxylase, providing more efficient serotonin precursor support than L-tryptophan alone.
How It Works
5-Hydroxytryptophan is produced in the body from the essential amino acid L-tryptophan. As the immediate precursor to serotonin (5-HT), it is decarboxylated in the central nervous system to elevate serotonin levels, which further influences melatonin production for sleep regulation, appetite control, and pain perception. Perfect for formulating advanced wellness products.
Primary Benefits & Use Scenarios
- Mood & Emotional Balance: Naturally boosts serotonin to support positive mood and reduce occasional stress.
- Restful Sleep: Precursor to both serotonin and melatonin, ideal for sleep-support formulations.
- Appetite & Weight Management: Enhances satiety and helps curb emotional eating in weight-management products.
- Other Wellness Applications: Suitable for formulas targeting nervous system health, fibromyalgia, or migraine support.
Product Highlights
- High-purity 5-Hydroxytryptophan powder (99%+ assay)
- Sourced from Griffonia simplicifolia for optimal bioavailability
- Excellent flowability and solubility
- Non-GMO, vegan, gluten-free, third-party tested for heavy metals, microbial limits, and potency
- Available in bulk packaging (custom quantities & MOQ available)
Suggested Use: For manufacturing and formulation only. Typical usage level: 50–200 mg per serving in finished dietary supplements (capsules, tablets, powders, or gummies). Not for direct consumer consumption in raw form.
Important Safety Note: This is a raw material ingredient for further processing and is not intended to diagnose, treat, cure, or prevent any disease. Final products must comply with local regulations (e.g., FDA, EU, etc.). Consult a qualified formulator or regulatory expert before use. Do not combine with other serotonin-elevating substances in finished products to avoid potential serotonin syndrome. Keep out of reach of children. Store in a cool, dry place away from light.
Authoritative Sources (for reference and credibility):
- PubChem (National Center for Biotechnology Information): Compound summary for 5-Hydroxytryptophan (CAS 56-69-9). https://pubchem.ncbi.nlm.nih.gov/compound/5-Hydroxytryptophan
- Wikipedia: 5-Hydroxytryptophan entry. https://en.wikipedia.org/wiki/5-Hydroxytryptophan
- WebMD: 5-HTP overview. https://www.webmd.com/vitamins/ai/ingredientmono-794/5-htp
- PMC Review (Maffei, 2020): https://pmc.ncbi.nlm.nih.gov/articles/PMC7796270/
Premium raw material for superior serotonin support formulations — elevate your product line with high-purity 5-Hydroxytryptophan Powder!
