Chitosan – High-Quality Chitosan Manufacturer & Supplier – Versatile Biopolymer

Applications

Medical Field

1. Drug Delivery
   • Due to its diverse properties, such as biodegradability, biocompatibility, antibacterial activity, non-toxicity, chitosancan be used as a suitable material for scaffold and nonopartical. The chitosan scaffolds and chitosan-based nanoparticles can deliver drug to a specific place in the body providing a controlled release, thus can be used to treat various diseases such as cancer, bone tissue regeneration, and repairs
2. Antibacterial and Anti-infective Properties
   • Chitosan exhibits broad-spectrum antibacterial activity, effectively inhibiting the growth of various pathogenic microorganisms, including bacteria and fungi.
   • In the medical field, chitosan is often used in the production of antibacterial ointments, sprays, and other products suitable for skin infections and wound treatment. It disrupts the bacterial cell membrane structure, inhibiting bacterial growth and reproduction, thereby reducing infection symptoms.
3. Wound Healing
   • Chitosan has the ability to promote cell regeneration, accelerating the wound healing process.
   • Applying chitosan-containing dressings or ointments to wounds helps reduce scar formation, maintain wound moisture, and promote skin tissue regeneration.
4. Immune Regulation
   • Chitosan can stimulate the activity of immune cells, enhancing the body's resistance to pathogenic microorganisms.
   • By regularly taking chitosan supplements and maintaining a healthy lifestyle, individuals can strengthen their immune system function and improve overall body resistance.
5. Blood Sugar and Lipid Regulation
   • Chitosan can slow down the rate of blood sugar increase and positively affect insulin secretion and sensitivity, thereby aiding in more effective blood sugar regulation.
   • Additionally, chitosan can adsorb cholesterol and fats, helping to lower lipid levels and prevent the occurrence of cardiovascular diseases.

Food and Health Supplements Field

1. Gut Health
   • Chitosan and its derivatives, such as chitooligosaccharides, can act as prebiotics, promoting the growth of beneficial gut bacteria.
   • By consuming an appropriate amount of chitosan, individuals can regulate their gut microbiota, maintain gut flora balance, and promote gut health.
2. Antioxidant and Anti-aging
   • Chitosan and its derivatives exhibit antioxidant activity, neutralizing free radicals, reducing oxidative stress, and protecting cells from oxidative damage.
   • This characteristic makes chitosan a potential candidate for use in anti-aging supplements.
3. Improving Taste and Texture
   • Chitosan and its derivatives can also be used as food additives for the preparation of microcapsules containing lactic acid bacteria, enzymes, vitamins, etc.
   • Additionally, they can serve as thickening agents and stabilizers, increasing food viscosity and texture, and improving food taste and flavor.

 

Biomedical applications of chitosan scaffold (Gholap AD, 2024)

The most popular ways of chitosan nanoparticles (ChNPs) applications.（Jafernik K, 2023）

References

Abd El-Hack ME, El-Saadony MT, Shafi ME, Zabermawi NM, Arif M, Batiha GE, Khafaga AF, Abd El-Hakim YM, Al-Sagheer AA. Antimicrobial and antioxidant properties of chitosan and its derivatives and their applications: A review. Int J Biol Macromol. 2020 Dec 1;164:2726-2744. 

Czarnek K, Ekiert H, Wiącek AE, Szopa A. Chitosan-Based Nanoparticles as Effective Drug Delivery Systems-A review. Molecules. 2023 Feb 18;28(4):1963.

Gholap AD, Rojekar S, Kapare HS, Vishwakarma N, Raikwar S, Garkal A, Mehta TA, Jadhav H, Prajapati MK, Annapure U. Chitosan scaffolds: Expanding horizons in biomedical applications. Carbohydr Polym. 2024 Jan 1;323:121394. 

Pizzolitto C, Vecchies F, Marfoglia A, Marsich E, Donati I. Glycosylated-Chitosan Derivatives: A Systematic Review. Molecules. 2020 Mar 27;25(7):1534

Cohen E, Poverenov E. Hydrophilic Chitosan Derivatives: Synthesis and Applications. Chemistry. 2022 Dec 1;28(67):e202202156.

Aghbashlo M, Amiri H, Moosavi Basri SM, Rastegari H, Lam SS, Pan J, Gupta VK, Tabatabaei M. Tuning chitosan's chemical structure for enhanced biological functions. Trends Biotechnol. 2023 Jun;41(6):785-797.

Maleki Dana P, Hallajzadeh J, Asemi Z, Mansournia MA, Yousefi B. Chitosan applications in studying and managing osteosarcoma. Int J Biol Macromol. 2021 Feb 1;169:321-329.

Riseh RS, Hassanisaadi M, Vatankhah M, Babaki SA, Barka EA. Chitosan as a potential natural compound to manage plant diseases. Int J Biol Macromol. 2022 Nov 1;220:998-1009

Mushtaq A, Li L, A A, Grøndahl L. Chitosan Nanomedicine in Cancer Therapy: Targeted Delivery and Cellular Uptake. Macromol Biosci. 2021 May;21(5):e2100005.

Boamah PO, Onumah J, Aduguba WO, Santo KG. Application of depolymerized chitosan in crop production: A review. Int J Biol Macromol. 2023 Apr 30;235:123858.

Product Advantages

• High Purity and Quality: As a dedicated chitosan manufacturer, GOTHINK Biotech ensures our chitosan is produced under stringent quality control measures, resulting in a product of high purity suitable for various applications.​

• Versatile Applications: Our chitosan is suitable for use in drug delivery systems, antibacterial products, wound healing dressings, immune support supplements, and as a food additive for gut health and texture improvement.​

• Scientifically Supported: The benefits of chitosan in medical, pharmaceutical, and food industries are well-documented in scientific literature, underscoring its efficacy and safety.

About us

GOTHINK Biotech stands as a global leader in synthetic biology, dedicated to harnessing the power of biology to discover and manufacture at scale the world's precious and scarce substances, addressing some of humanity's most pressing health challenges.​

Core Manufacturing Capabilities and Quality Assurance

• Advanced DNA Synthesis and Sequencing: Utilizing state-of-the-art technologies, we design and construct custom genetic pathways, enabling the creation of organisms with tailored functionalities.​
• CRISPR and Genome Editing: Our precision genome editing expertise allows us to engineer organisms with enhanced traits, accelerating the development of breakthrough therapies and sustainable bioproducts.​
• Metabolic Engineering: By optimizing metabolic pathways, we engineer microorganisms to produce high-value compounds, such as enzymes, pharmaceuticals, novel ingredients, and bio-based materials, with unparalleled efficiency.​
• Bioinformatics and AI-Driven Design: Our proprietary computational platforms integrate bioinformatics, machine learning, and artificial intelligence to model, simulate, and optimize biological systems, reducing development timelines and costs.​
• Synthetic Genomics: As pioneers in synthetic genomics, we design and assemble synthetic chromosomes and genomes, pushing the boundaries of biological engineering.​

Production Strengths

• Innovative Research & Development: Our state-of-the-art R&D facilities are at the forefront of synthetic biology, enabling us to design and engineer novel ingredients that promote human health. Our team of world-class scientists and researchers is committed to pushing the boundaries of what is possible, ensuring that our products are both effective and safe.​
• Regulatory Excellence: We adhere to the highest standards of quality and safety, ensuring that all our products meet rigorous regulatory requirements. Our commitment to compliance and transparency has earned us the trust of consumers and industry stakeholders alike.​

Sustainability Initiatives

Sustainability is at the heart of everything we do. We are committed to developing eco-friendly production processes that minimize environmental impact while maximizing the health benefits of our products. By integrating green chemistry and renewable resources, we strive to set new standards for sustainable innovation in the biotechnology industry.​

Client Collaboration Process

We engage in a collaborative approach with our clients, starting from understanding their specific needs, through research and development, to the final delivery of tailored solutions. Our process ensures transparency, efficiency, and alignment with client objectives.​

Global Service Capabilities

With a presence in key markets around the world, GOTHINK Biotech is uniquely positioned to deliver our health-enhancing ingredients to a diverse and growing customer base. Our global network of partners and collaborators allows us to stay ahead of industry trends and respond swiftly to the evolving needs of our clients.​

Partner with GOTHINK Biotech to leverage cutting-edge synthetic biology solutions that drive innovation and success in your endeavors.​

FAQ

Who are we?

GOTHINK Biotech is a global leader in synthetic biology, dedicated to harnessing the power of biology to discover and manufacture at scale the world's precious and scarce substances, addressing some of humanity's most pressing health challenges.

How can we guarantee quality?

We adhere to the highest standards of quality and safety, ensuring that all our products meet rigorous regulatory requirements. Our commitment to compliance and transparency has earned us the trust of consumers and industry stakeholders alike.

What can you buy from us?

We offer a range of high-value compounds, including enzymes, pharmaceuticals, novel ingredients, and bio-based materials, engineered through our advanced synthetic biology technologies.

Why should you buy from us and not from other suppliers?

Our state-of-the-art R&D facilities, world-class scientific team, and commitment to sustainability and regulatory excellence position us uniquely in the industry. We provide tailored, innovative solutions with a focus on quality and environmental responsibility.

What services can we provide?

We offer services in advanced DNA synthesis and sequencing, CRISPR and genome editing, metabolic engineering, bioinformatics and AI-driven design, and synthetic genomics, all aimed at developing customized solutions to meet our clients' specific needs.

Partner with GOTHINK Biotech for premium chitosan solutions. Contact us today to discuss your specific requirements and discover how our high-quality chitosan can enhance your products and applications.​