Pyruvic acid 

Application

1. Energy Supplement and Sports Nutrition
   As a core molecule in energy metabolism, pyruvic acid is widely used in sports nutrition products. Studies have shown that pyruvic acid supplementation can enhance exercise endurance and delay fatigue by improving glycolysis efficiency, promoting lactate clearance, and enhancing mitochondrial function. It is commonly added to energy drinks, sports supplements, and recovery products.
2. Weight Loss and Management
   Pyruvic acid has gained attention in weight loss products. Research indicates that it can promote fat metabolism, increase energy expenditure, and inhibit fat synthesis. Additionally, it improves insulin sensitivity, helping regulate blood sugar levels and reduce fat accumulation. Some weight loss supplements combine pyruvic acid with chromium and L-carnitine to enhance its effects.
3. Antioxidant and Anti-Aging
   The antioxidant properties of pyruvic acid make it a valuable ingredient in anti-aging health products. It protects cells from damage by scavenging free radicals and reducing oxidative stress, thereby slowing the aging process. Moreover, pyruvic acid promotes collagen synthesis, improving skin elasticity, and is used in beauty supplements.
4. Immune Support and Health Maintenance
   Pyruvic acid participates in multiple metabolic pathways, enhancing immune system function. For instance, it provides energy to support immune cell activity and reduces inflammation through its antioxidant effects. Therefore, it is often included in immune-boosting supplements to improve body resistance.
5. Cardiovascular Health
   Pyruvic acid also offers protective effects on the cardiovascular system. Studies have shown that it can lower blood lipid levels and reduce the risk of atherosclerosis. Its antioxidant properties further protect vascular endothelial cells and improve blood circulation.

References

1. Mallet RT, Olivencia-Yurvati AH, Bünger R. Pyruvate enhancement of cardiac performance: Cellular mechanisms and clinical application. Exp Biol Med (Maywood). 2018 Jan;243(2):198-210.
2. Koves TR, Zhang GF, Davidson MT, Chaves AB, Crown SB, Johnson JM, Slentz DH, Grimsrud PA, Muoio DM. Pyruvate-supported flux through medium-chain ketothiolase promotes mitochondrial lipid tolerance in cardiac and skeletal muscles. Cell Metab. 2023 Jun 6;35(6):1038-1056.e8.
3. Gray LR, Tompkins SC, Taylor EB. Regulation of pyruvate metabolism and human disease. Cell Mol Life Sci. 2014 Jul;71(14):2577-604.