Applications of L-Malic Acid
Food:
L-Malic acid enhances the acidity and taste of food, making it more delicious and pleasant.
It serves as a preservative and antioxidant, extending the shelf life of food and maintaining its freshness and nutritional value.
Pharmaceutical:
L-Malic acid is used as a raw material or excipient in the manufacture of oral solutions, injections, tablets, capsules, and other dosage forms.
It has antioxidant and antifatigue properties, making it suitable for use in the production of health supplements and pharmaceuticals to help improve the immune system and promote overall health.
When combined with composite amino acid injection solutions, L-malic acid enhances the utilization of amino acids, which is particularly important for post-operative patients and those with liver dysfunction.
Cosmetics:
L-Malic acid serves as a raw material in cosmetics, providing moisturizing, whitening, and anti-aging benefits.
It is used as a conditioning agent, moisturizer, antioxidant, softener, and exfoliant to improve skin quality and make it smoother and finer.
Agriculture:
L-Malic acid promotes plant growth and increases yield, while also improving fruit quality and disease resistance.
It serves as a plant growth regulator, providing necessary nutrients and growth regulators for plants to promote healthy growth and development.
Other Applications:
L-Malic acid is used in the synthesis of other chemicals, such as polylactic acid and other biodegradable materials, contributing to environmental protection.
In the tobacco industry, malic acid derivatives (such as esters) can improve tobacco flavor and enhance the quality of tobacco products.
Methods for malic acid production and applications of malic acid and its derivatives in different industries. (Wu N, et al, 2022)
References:
Wu N, Zhang J, Chen Y, Xu Q, Song P, Li Y, Li K, Liu H. Recent advances in microbial production of L-malic acid. Appl Microbiol Biotechnol. 2022 Dec;106(24):7973-7992.
Lu W, Sun X, Gao L, Hu X, Song H, Kong B (2022) Study on the characteristics and mechanism of DL-malic acid in inhibiting spontaneous combustion of lignite and bituminous coal. Fuel 308:122012.
Yan E, Wang Y, He L, Guo J, Zhang X, Yin J. Effects of Dietary L-malic Acid Supplementation on Meat Quality, Antioxidant Capacity and Muscle Fiber Characteristics of Finishing Pigs. Foods. 2022 Oct 24;11(21):3335.
Kim HO, Lum C, Lee MS (1997) Malic acid: a convenient precursor for the synthesis of peptide secondary structure mimetics. Tetrahedron Lett 38(28):4935–4938
Yin X, Li JH, Shin HD, Du GC, Liu L, Chen J (2015) Metabolic engineering in the biotechnological production of organic acids in the tricarboxylic acid cycle of microorganisms: advances and prospects. Biotech Adv 33(6):830–841
Glenn JM, Gray M, Wethington LN, Stone MS, Stewart RW Jr, Moyen NE (2017) Acute citrulline malate supplementation improves upper- and lower-body submaximal weightlifting exercise performance in resistance-trained females. Eur J Nutr 56(2):775–784
Zhang Z, Wang B, Zhou P, Guo D, Kang R, Zhang B (2016) A novel approach of chemical mechanical polishing using environment-friendly slurry for mercury cadmium telluride semiconductors. Sci Rep 6:22466
Liu J, Li J, Shin H-D, Liu L, Du G, Chen J (2017b) Protein and metabolic engineering for the production of organic acids. Bioresource Technol 239:412–421.
Li Z-J, Hong P-H, Da Y-Y, Li L-K, Stephanopoulos G (2018) Metabolic engineering of Escherichia coli for the production of L-malate from xylose. Metab Eng 48:25–32
Kang NK, Lee JW, Ort DR, Jin YS. L-malic acid production from xylose by engineered Saccharomyces cerevisiae. Biotechnol J. 2022 Mar;17(3):e2000431.
Schmitt V, Derenbach L, Ochsenreither K. Enhanced l-Malic Acid Production by Aspergillus oryzae DSM 1863 Using Repeated-Batch Cultivation. Front Bioeng Biotechnol. 2022 Jan 10;9:760500.
High Quality and Purity: GOTHINK Biotech ensures that all L-Malic Acid products meet stringent quality standards, offering a pure and highly effective ingredient for diverse industrial applications.
Versatile Applications: Suitable for use in food, pharmaceuticals, cosmetics, and agriculture, L-Malic Acid serves various sectors with its multifunctional properties.
Scientifically Supported: The benefits of malic acid are backed by research, ensuring its efficacy in enhancing flavor, improving product stability, and supporting health and growth.
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